Folate is a variety of vitamin B which is water-soluble and formerly known as Vitamin B9, one of the major elements supporting humans to maintain human health and improves human metabolism. Folate is expected to function as key in the metabolism of nucleic acids and amino acids too. Folate is technically termed as Pteroylglutamic acid, which is differently termed as Folvite, folacin, Acifolic, Vitamin M, and Folcidin.
Lucy Wills has observed the nutritional importance of vitamin B9 or folate in the year 1931 when she was performing her research in Bombay, India, on pregnant women. Her studies made a note that these pregnant ladies were macrocytic anemia patients. Vitamin B9 was first observed from the variety of green leafy vegetables Spinach in the year 1941. The pure crystalline form of the Folate was invented by Stokstad in the year 1943.
Folate is chemically structured as 2 amino-4hydroxy-pteridine linked with the methylene bridge to p-aminobenzoyl group. This turned through amide linkage into polyglutamate or glutamic acid. Synthetic folate is widely used in the preparation of food substances which are essential for human health and used as supplements for health disordered public. These folates are isolated and approved by scientists for balancing human life with all the essential elements for the health of humans.